Anouk EWEN
Title: K63-linked Ubiquitination in the Innate Immune Response Ubiquitination is a post-translational protein modification that critically regulates initiation,propagation and termination of the innate immune response. The ubiquitin-conjugating E2 enzyme 13 (Ubc13) catalyzes K63-linked polyubiquitin chains, which have non-proteolytic functions such asthe recruitment of binding partners. Ubc13-mediated ubiquitination plays an important role in NF-κBsignaling and is … Continued