After graduating from the Università degli Studi di Milano (Italy), Dr. Cosma pursued a PhD in Human Biology at the Faculty of Medicine of the Ludwig-Maximilians-Universität (Germany). From 2009 to 2018, he headed the FlowCyTech core facility at the Atomic Energy Commission during which he obtained the Accreditation to Direct Research from the “Université Paris-Sud” (France). Currently he heads the Biospecimen Services & Data Generation unit at the LIH and is in charge of the National Cytometry Platform (NCP). For many years his scientific activity focused on the study of the immune system during HIV infection. In 2011, he was leading the first core facility in Europe to implement the mass cytometry. Mass cytometry (or Cytometry by Time Of Flight: CyTOF) combines flow cytometry and mass spectrometry to achieve the simultaneous single cell measurement of more than 50 markers (commonly proteins). He used the CyTOF for the comparative analysis of the immune system in humans and in the Cynomolgus macaque model, and the characterization of the innate immune system in infectious diseases, vaccination models and inflammatory diseases. He is an expert in the development of flow-cytometry-based assays, data management and analysis. His prime goal is to facilitate multidimensional data analysis by merging the fields of flow cytometry and Business Intelligence. He recently proposed a new method for the annotation of cell types based on prime numbers and the fundamental theorem of arithmetic. He is active in the single cell community in organizing workshops and trainings, and he is an Associate Editor for the journal Cytometry A.