The workshops run in parallel.

Only attend one of the workshops and do not jump between the sessions.

Thank you!

DAY 1

Thursday, 7 October 2021 | 14:00 - 15:00

Workshop Booth 1

Flow Cytometry basics and panel design

Patrick Bier

After performing research in different Universities in Amsterdam Patrick Bier moved to the industry to work at Sanquin to focus on assay development. After a few years in this field he moved to a more sales driven role focusing on the antibodies. With the experience moving more to immunology and flow cytometry in general he started with eBioscience being the first person to sell direct in the Benelux. After several acquisitions he decided to move to BioLegend to work in an even more technical environment where he now is in the main contact for the Benelux for both technical and price related questions as a Technical Sales Specialist.

In this workshop you will learn more on the Flow Cytometry basics and all the features needed for a successful panel design. These basics in mind, what considerations should that be made for the most optimal design. You will be shown an example of a design made in the workshop as a live session. This workshop is tailored for the needs discussed with the organisers and suitable for people both new and experienced in Flow Cytometry.

Interesting Links:

https://www.biolegend.com

https://www.biolegend.com/fr-lu/flow-cytometry-tools

Workshop Booth 2

Computational approaches to delineate disease-specific pathways in the multi-omics era

Srikanth Ravichandran

The workshop will focus on how to leverage clinical omics data to understand complex diseases. In particular, I will talk about how computational approaches, that include both novel machine learning techniques, and traditional modelling strategies, can aid developing effective drugs for inflammatory diseases.

DAY 2

Friday, 8 October 2021 | 13:30 - 14:30

Workshop Booth 1

Multidimensional Data Analysis

Antonio Cosma

After graduating from the Università degli Studi di Milano (Italy), Dr. Cosma pursued a PhD in Human Biology at the Faculty of Medicine of the Ludwig-Maximilians-Universität (Germany). From 2009 to 2018, he headed the FlowCyTech core facility at the Atomic Energy Commission during which he obtained the Accreditation to Direct Research from the “Université Paris-Sud” (France). Currently he heads the Biospecimen Services & Data Generation unit at the LIH and is in charge of the National Cytometry Platform (NCP). For many years his scientific activity focused on the study of the immune system during HIV infection. In 2011, he was leading the first core facility in Europe to implement the mass cytometry. Mass cytometry (or Cytometry by Time Of Flight: CyTOF) combines flow cytometry and mass spectrometry to achieve the simultaneous single cell measurement of more than 50 markers (commonly proteins). He used the CyTOF for the comparative analysis of the immune system in humans and in the Cynomolgus macaque model, and the characterization of the innate immune system in infectious diseases, vaccination models and inflammatory diseases. He is an expert in the development of flow-cytometry-based assays, data management and analysis. His prime goal is to facilitate multidimensional data analysis by merging the fields of flow cytometry and Business Intelligence. He recently proposed a new method for the annotation of cell types based on prime numbers and the fundamental theorem of arithmetic. He is active in the single cell community in organizing workshops and trainings, and he is an Associate Editor for the journal Cytometry A.

Flow cytometry is able to measure multiple markers at the single event level. In the field of immunology, it is often used to measure the expression of relevant markers on single cells. The amount of data generated is constantly increasing over time, since new technologies such as the spectral flow cytometry and the mass cytometry allow for the measurement of more than 40 markers on a single cell. Each sample may contain millions of single cells and often this data need to be related to metadata and data generated by other omics technologies. This amount of data requires the implementation of data reduction tools and technologies for easy integration of multiple kind of data-sets. I will present an overview of the quality controls needed before starting your analysis. I will explain the basic concepts of data reduction together with some real examples. Finally, I will show an innovative way for data cleaning and integration using tools generally used in the business sector (Business Intelligence).

Workshop Booth 2

A journey from academic research to the creation of a startup

Vincent Puard

Most of experience, skills and network acquired during a PhD or a post-doc might seemed only related to science and a specific field that you are, or becoming, an expert. During the presentation Vincent will share how he started as a PhD student in biology to be a co-founder of a startup developing antibody drugs using Artificial Intelligence. While having worked in academic labs and biotech in Europe as head of protein array platform, he learned the processes and mindset of the two worlds. His meetings with many researchers and entrepreneurs over the world allowed him to gather different point of view and forge his path to the creation of MAbSilico who he is now CEO. Even if research is not his daily work, knowing the industry and the state of the art technologies are essential. Finding the best team to begin a company and make it growths is the key to success and can be done by relying on experience and network built over years. Vincent will share this journey with you and focus on what PhD can do in a startup and in industry more generally.

 

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